Table 3 Main outcomes and clinical parameters at the end of the study period.
Parameter | Group | P-value | ||
|---|---|---|---|---|
Favipiravir | Hydroxychloroquine | Standard Care | ||
N | 54 | 51 | 52 | |
Clinical scale < 2, N = 149 # [n(%)] | 45 (84.9%) | 44 (89.8%) | 42 (89.4%) | 0.702 |
Viral Clearance, N = 118 # [n(%)] | 32 (80%) | 31 (81.6%) | 26 (65%) | 0.168 |
Median length of hospital stay, days [median (IQR)] * | 6 (4, 9) | 6 (4, 8) | 7 (4.5,9) | 0.126 |
SOFA Scale Score, [median (IQR)] | 0.0 (0.0, 0.1) | 0.0 (0.0, 0.3) | 0.0 (0.0, 0.3) | 0.42 |
NEWS2 Scale Score, [median (IQR)] | 0.0 (0.0, 1.0) | 1.0 (0.0, 2.0) | 0.0 (0.0, 1.0) | 0.20 |
FiO2 (fraction of inspired oxygen), [median (IQR)] | 0.2 (0.2, 0.2) | 0.2 (0.2, 0.2) | 0.2 (0.2, 0.2) | 0.39 |
Temperature (C), [median (IQR)] | 36.7 (36.6, 36.9) | 36.6 (36.5, 36.8) | 36.7 (36.6, 36.8) | 0.22 |
Diastolic BP (mmHg), [median (IQR)] | 72 (69, 80) | 68 (63, 74) | 76 (68, 82) | 0.005 |
Systolic BP (mmHg), [median (IQR)] | 120 (110, 129) | 115 (107, 123) | 125 (113, 134) | 0.005 |
Respiratory Rate (breaths/min), [median (IQR)] | 20.0 (18.0, 20.0) | 18.0 (18.0, 20.0) | 18.0 (18.0, 20.0) | 0.81 |
Heart Rate (beats/min), [median (IQR)] | 78.0 (68.0, 84.0) | 75.0 (70.0, 82.0) | 78.0 (72.0, 84.0) | 0.67 |
Oxygen Saturation (mm Hg), [median (IQR)] | 98.0 (97.0, 99.0) | 98.0 (97.0, 99.0) | 97.0 (97.0, 99.0) | 0.12 |
