Figure 3
From: Female hormones prevent sepsis-induced cardiac dysfunction: an experimental randomized study
Left ventricular JAK2 expression and STAT3 phosphorylation assessed by western-blot in sham (n = 5), sepsis (n = 4), sepsis plus landiolol (n = 4), OVR-sham (n = 5), OVR-sepsis (n = 5) and OVR-sepsis plus landiolol (n = 4). (A) JAK2 expression. (B) STAT3-Tyr705 phosphorylation. (C) The phosphorylation of STAT3 and the expression of JAK2 were normalized to actin on stripped blot. (D) STAT3-Ser727 phosphorylation. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 vs sham and vs OVR-sham, respectively. §p < 0.05 vs OVR-sepsis. ††p < 0.01; ††††p < 0.0001 vs control of corresponding group.
