Table 4 Short-term neonatal morbidity of newborns from pregnancies with PPROM with respect to intra-amniotic infection, sterile intra-amniotic inflammation, colonization, and negative amniotic fluid.

From: Clinical characteristics of colonization of the amniotic cavity in women with preterm prelabor rupture of membranes, a retrospective study

Characteristic

Intra-amniotic Infection (n = 37)

Sterile intra-amniotic inflammation (n = 21)

Colonization of the amniotic cavity (n = 32)

Negative amniotic fluid (n = 212)

p value1

p value1#

p value2

p value2#

p value3

p value3#

Need for intubation [number (%)]

2 (5%)

0 (0%)

1 (3%)

5 (2%)

1.00

0.99

1.00

0.34

0.57

0.73

Respiratory disorders

19 (51%)

10 (48%)

7 (22%)

56 (26%)

0.01

0.94

0.07

0.89

0.67

0.59

Respiratory distress syndrome [number (%)]

19 (51%)

9 (43%)

6 (19%)

43 (20%)

0.006

0.72

0.07

0.96

1.00

0.91

Transient tachypnea of newborns

0 (0%)

1 (5%)

1 (3%)

13 (6%)

0.46

0.15

1.00

0.70

0.70

0.51

Intraventricular hemorrhage [number (%)]

7 (19%)

5 (24%)

3 (9%)

18 (9%)

0.32

0.89

0.24

0.83

0.74

0.83

intraventricular hemorrhage grade I-II [number (%)]

5 (14%)

5 (24%)

3 (9%)

17 (8%)

0.72

0.81

0.24

0.83

0.74

0.77

Intraventricular hemorrhage grade III-IV [number (%)]

2 (5%)

0 (0%)

0 (0%)

1 (1%)

0.50

0.45

–

–

1.00

0.72

Necrotizing enterocolitis [number (%)]

1 (3%)

1 (5%)

0 (0%)

0 (0%)

1.00

0.98

0.40

0.89

–

–

Intestinal perforation [number (%)]

1 (3%)

1 (5%)

0 (0%)

0 (0%)

1.00

0.89

0.40

0.89

–

–

Early-onset sepsis [number (%)]

3 (8%)

2 (10%)

1 (3%)

3 (2%)

0.62

0.85

0.55

0.40

0.43

0.47

Late-onset sepsis [number (%)]

1 (3%)

0 (0%)

0 (0%)

0 (0%)

1.00

0.98

–

–

–

–

Pneumonia [number (%)]

2 (5%)

0 (0%)

1 (3%)

1 (1%)

1.00

0.69

1.00

0.34

0.25

0.11

Bronchopulmonary dysplasia [number (%)]

9 (24%)

3 (14%)

0 (0%)

5 (2%)

0.003

0.78

0.06

0.83

1.00

0.38

Retinopathy of prematurity [number (%)]

4 (11%)

2 (10%)

0 (0%)

4 (2%)

0.12

0.97

0.15

0.88

1.00

0.45

Death before discharge [number (%)]

3 (8%)

0 (0%)

0 (0%)

2 (1%)

0.24

0.84

–

–

1.00

0.60

Compound neonatal morbidity [number (%)]

22 (60%)

12 (57%)

10 (31%)

65 (31%)

0.03

0.58

0.09

0.95

1.00

0.82

  1. Variables were compared using the Fisher’s exact test and are presented as number (%). Statistically significant results are marked in bold.
  2. p-value1—comparison between women with colonization of the amniotic cavity and with intra-amniotic infection.
  3. p-value2—comparison between women with colonization of the amniotic cavity and with sterile intra-amniotic inflammation.
  4. p-value3—comparison between women with colonization of the amniotic cavity and with negative amniotic fluid.
  5. # the results were adjusted for gestational age at sampling.
Back to article page