Figure 4 | Scientific Reports

Figure 4

From: In vitro culture at 39 °C during hepatic maturation of human ES cells facilitates hepatocyte-like cell functions

Figure 4

Global transcriptional analysis to identify the specific gene signatures in hESC-HLCs with heat treatments at 37 °C and 39 °C. (A) Hierarchical clustering and heat map of the differentially expressed genes in hESC-HLCs with heat treatments at 37 °C and 39 °C. (B) Typical plots of five clusters identified in (A). Each dot represents the median of expression values of each sample. (C) Chord diagram presenting enriched GO clusters for the differentially expressed genes hESC-HLCs with heat treatment at 37 °C and 39 °C. In each chord diagram, enriched GO clusters are shown (right), and genes contributing to this enrichment shown (left). Each cluster was found in (A).

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