Table 1 Preparation of various Niosome-encapsulated imipenem formulations.
Formulations | Different compounds of surfactant:cholesterol | Span + tween + cholesterol molar ratio | Span:tween molar ratio | Drug concentration (mg/ml) |
---|---|---|---|---|
Different formulations of Niosomal Imipenem | ||||
F1 | Span 60 + Tween 60 + Cholesterol | 3:3:4 | 50:50 | 1 |
25:75 | 1 | |||
75:25 | 1 | |||
F2 | Span 40 + Tween 40 + Cholesterol | 3:3:4 | 50:50 | 1 |
25:75 | 1 | |||
75:25 | 1 |