Figure 5

Relative transcript abundance of genes involved in cholesterol biosynthesis ((a) hmgcs1; (b) lxr; (c) cyp7a, (d) miRNA-122-5p) in tissues of normoxic controls (N), 1-week hypoxic (1WH) and 4-week hypoxic (4WH) goldfish. Values are means ± standard error of the mean (s.e.m.); sample size = 7–12 per group. Differences between normoxia and chronic hypoxia are indicated as *(p < 0.05), **(p < 0.01) and ***(p < 0.001). Differences between 1 and 4WH are indicated as ##(p < 0.01) and ###(p < 0.001).