Figure 4
Social test in as a function of age and DM exposure in Chd8V986*/+ mice. Mice were tested at 6 and 12 months of age. (a–d) Sociability assessed by the time spent in 5 cm proximity to a caged stranger or an empty cage. (e–h) Social novelty preference tested by the time spent in 5 cm proximity to each caged stranger mouse. Bars represent mean ± S.E.M. for a 10 min test. N = 10–12 mice per group. Fisher’s PLSD tests were used for comparing group means only when a significant F value was determined by using a two-way repeated measures ANOVA for each exposure and age group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
