Table 2 Clinical and physiological comparisons between subgroups defined based on symptoms and physical activity questionnaires.

From: Associations of pulmonary and extrapulmonary computed tomographic manifestations with impaired physical activity in symptomatic patients with chronic obstructive pulmonary disease

 

Less symptomatic (CAT < 10)

Symptomatic (CAT ≥ 10)

 

LSA > 60

(n = 82)

LSA ≤ 60

(n = 11)

LSA > 60

(n = 73)

LSA ≤ 60

(n = 27)

Age

72.1 ± 6.4

74.0 ± 6.9

71.9 ± 8.4

74.3 ± 9.6

Male, n (%)

79 (96%)

9 (82%)

67 (92%)

25 (93%)

Pack-years

60.0 ± 30.7

76.1 ± 39.2

57.8 ± 28.7

60.9 ± 33.7

Height, cm

166.7 ± 6.5

160.2 ± 8.4

164.9 ± 6.9

163.3 ± 8.3

BMI, kg/m2

23.8 ± 3.2

23.3 ± 3.0

23.6 ± 3.6

20.0 ± 4.2*†‡

No. exacerbations in a previous year, 0/1/ ≥ 2

68/13/1

11/0/0

50/19/4

19/5/3

FEV1, % predicted

69.1 ± 20.4

71.3 ± 16.1

60.4 ± 23.3

45.4 ± 19.3*†‡

FVC, % predicted

95.0 ± 20.5

90.4 ± 6.4

87.9 ± 2.5

75.2 ± 4.1*‡

GERD

7 (9%)

2 (18%)

21 (29%) *

3 (11%)

Allergic rhinitis

10 (12.1%)

0 (0%)

12 (16.4%)

1 (3.7%)

Hypertension

41 (50%)

5 (45%)

48 (66%)

11 (41%)

IHD

13 (16%)

1 (9%)

12 (16%)

1 (4%)

DM

9 (11%)

2 (18%)

12 (16%)

2 (7%)

LAMA use, n (%)

43 (52%)

7 (64%)

46 (63%)

23 (85%) *

LABA use, n (%)

46 (56%)

5 (45%)

52 (71%)

20 (74%)

ICS use, n (%)

32 (39%)

2 (18%)

37 (51%)

11 (41%)

  1. Data are expressed as mean ± SD and n (%). Based on scores of COPD assessment test (CAT) and Life-Space Assessment (LSA) questionnaires, patients were divided into 4 groups. IHD = ischemic heart disease, GERD = gastroesophageal reflex disease, DM = diabetes mellitus, LAMA = long-acting muscarinic antagonist, LABA = long-acting beta agonist, ICS = inhaled corticosteroid. * p < 0.05, †p < 0.05, and ‡ p < 0.05 compared to patients with CAT < 10 and LSA > 60, to those with CAT < 10 and LSA ≤ 60, and to those with CAT ≥ 10 and LSA > 60, respectively, based on the Tukey’s method for continuous variables and Fisher’s exact tests with Bonferroni correction for categorical variables.
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