Figure 8

Bioinformatics analysis of DEPs. All 522 DEPs underwent the analysis of subcellular localization (A), the enrichment analysis of KEGG signaling pathways (B) and Gene Ontology annotation (C). (D) The DEPs in the “Proteoglycans in cancer” KEGG pathway. (E) Western blot analysis of TGF-β2, SMAD2, and p-SMAD2 in PANC-1 cells treated with or without rhoifolin. GAPDH was used as internal reference.