Figure 7 | Scientific Reports

Figure 7

From: Misfolding-induced chronic pancreatitis in CPA1 N256K mutant mice is unaffected by global deletion of Ddit3/Chop

Figure 7

Fibrosis in the pancreas of CPA1 N256K × Ddit3-KO mice. (A) Masson’s trichrome staining of pancreas sections from 3-month-old C57BL/6N, Ddit3-KO, CPA1 N256K, and CPA1 N256K × Ddit3-KO mice. Collagen is stained blue. The scale bar corresponds to 50 µm. (B) Hydroxyproline content of the pancreas from C57BL/6N (n = 4 and 6), Ddit3-KO (n = 4 and 6), CPA1 N256K (n = 7 and 10), and CPA1 N256K × Ddit3-KO (n = 6 and 10) mice at 3 months and 6 months of age. Individual data points with mean (horizontal bar) and standard deviation are shown.

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