Table 2 Optimal weighted λ–superstring, λ values, and VaxiJen overall prediction for the two candidate vaccines with the maximum λ value.

From: First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine

Length

Lambda

Prediction

Sequence

22

8.03

0.5545

1:STQDLFLPFFSNVTWFHAIHVS(NTD)

277

122.44

0.5190

1:QSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNC(CD)

2:TEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQ

3:DLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSK(NTD)

4:FLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSN

5:FRVQPTESIVRFPNITNLCPFGEVFNATRFASVYA(RBD)

  1. Column 1, the number of amino acids in the CVs; column 2, the value of λ; column 3, the VaxiJen overall prediction for antigenicity; column 4, the peptides whose union forms the λ-superstring.
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