Figure 6 | Scientific Reports

Figure 6

From: Optimization, validation and initial clinical implications of a Luminex-based immunoassay for the quantification of Fragile X Protein from dried blood spots

Figure 6

FXP concentrations are consistent over time. (a) Repeated bi-weekly FXP levels in 12 adults with FM FXS (9 males; 3 females) showed consistency over 13 weeks (ICC value 98.8), (b) Over longer intervals between FXP testing (mean 11 months; range 0.5–30 months), within subject FXP levels showed consistency (ICC value 97.6) in 25 persons (18 males, 7 females; age range 0.5–49.8 years) across all diagnostic categories. Note that study 3 included multiple fully methylated FM males with undetectable FXP levels. FXP Fragile X Protein, FM Full Mutation, FXS Fragile X Syndrome, ICC Intra-Class Correlation Coefficient.

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