Table 2 SARS-CoV-2 clearance in patients treated with SOF/VEL and in untreated patients.

Number

30

90

Duration of infection before antiviral treatment (days of PCR positive), median (range)

6 (3–13)

7 (4–14)*

ns

Days of SARS-CoV-2 Clearance by first positivity, median (range)

14 (6–23)

22 (7–55)

0.001

Days of SARS-CoV-2 Clearance by starting SOF/VEL, median (range)

6 (5–21)

22 (7–55)

0.0001

SARS-CoV-2 clearance

 ≤ 7 days, %

50

1.1

0.001

 ≤ 14 days, %

83

13

0.001

 ≤ 21 days, %

93

38

0.001

 ≤ 27 days, %

100

67.3

0.001

Clinical outcome

Disease progression, %

0

24

0.001

Mortality, %

0

1.1

ns