Table 2 Summary of myocardial microscopic changes of note.
Microscopic finding/group | MI-SSO2 | MI-Sham | Non-MI-SSO2 | Non-MI-Sham | MI-SSO2 | MI-Sham | Non-MI-SSO2 | Non-MI-Sham |
|---|---|---|---|---|---|---|---|---|
Time point (Days) | Day 7 | Day 30 | ||||||
Number of animals examined | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Mixed cell infiltrate | 8 | 2 | 1 | 3 | 14 | 13 | 24 | 9 |
Score 1 | 8 | 2 | 1 | 3 | 14 | 13 | 24 | 7 |
Score 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
Infarct scar | 66 | 76 | 2 | 2 | 32 | 53 | 5 | 4 |
Score 1 | 43 | 57 | 2 | 1 | 29 | 49 | 5 | 4 |
Score 2 | 23 | 19 | 0 | 1 | 3 | 4 | 0 | 0 |
Number of animals with finding at any level | 5 | 5 | 2 | 2 | 5 | 5 | 2 | 1 |
Microgranuloma | 0 | 3 | 0 | 1 | 9 | 5 | 1 | 3 |
Score 1 | 0 | 3 | 0 | 1 | 9 | 5 | 1 | 3 |
Foreign body microembolus | 2 | 3 | 4 | 3 | 12 | 4 | 2 | 9 |
Score 1 | 2 | 3 | 4 | 3 | 11 | 4 | 1 | 8 |
Score 2 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Depletion, myocardial fibers | 2 | 4 | 10 | 4 | 21 | 7 | 5 | 8 |
Score 1 | 2 | 4 | 8 | 4 | 21 | 7 | 4 | 7 |
Score 2 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 1 |
Thrombus | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Total number of myocardial regions examined per animal | 42 | 42 | 42 | 42 | 42 | 42 | 42 | 42 |
Total number of myocardial regions examined per group | 210 | 210 | 210 | 210 | 210 | 210 | 210 | 210 |
