Figure 2

A thyroid nodule, assigned to Bethesda category III, was considered benign diagnosed by the combination of TIRADS and BRAFV600E analysis. The nodule proved to be a benign one confirmed by postoperative pathology. (a), the 2D sonogram classified as TIRADS 4a, (b), wild-type BRAFV600E gene, (c), nodular goiter confirmed by postoperative pathology.