Figure 4

Representative images of a 63-year-old man with a body mass index of 22.2 kg/m2 and 75 kg body weight who underwent 2-[18F]FDG PET/CT for re-staging of esophageal cancer. CT images (A) show a newly developing 5 mm nodule in the right upper lobe. Subjective image quality ratings (B) of reader 1 and reader 2 for ordered subset expectation maximization (OSEM) and block sequential regularized expectation maximization (BSREM) reconstruction images indicate an increased lesion conspicuity. Axial slices at the same level showing OSEM reconstruction (C,D) and BSREM reconstruction (E,F) show the 2-[18F]FDG-avid nodule.