Table 2 Results of quantitative PET image assessment, including maximum standardized uptake value (SUVmax) of the lung nodules (n = 144), nodule signal-to-background ratio (SBR), nodule signal-to-noise ratio (SNR), contrast-to-background ratio (CBR), and contrast-to-noise ratio (CNR) in block sequential regularized expectation maximization (BSREM) compared to ordered subset expectation maximization (OSEM) reconstructions as reference.

From: Impact of Bayesian penalized likelihood reconstruction on quantitative and qualitative aspects for pulmonary nodule detection in digital 2-[18F]FDG-PET/CT

 

BSREM

OSEM

p valuea

SUVmax

  

0.0001

Mean

5.4

3.6

 

Median

4.0

2.7

 

Range

1.2–20.7

0.7–17.4

 

SBR

  

0.0001

Mean

3.3

2.2

 

Median

2.4

1.6

 

Range

0.7- 15.7

0.4–8.6

 

SNR

  

0.0001

Mean

21.2

14.6

 

Median

15.9

10.5

 

Range

3.9–89.4

2.5–75.7

 

CBR

  

0.0001

Mean

1.2

0.3

 

Median

0.54

− 0.06

 

Range

− 0.6 to 14.7

− 0.8 to 4.5

 

CNR

  

0.0001

Mean

7.1

2.1

 

Median

3.0

− 0.4

 

Range

− 4.9 to 67.1

− 7.2 to 37.8

 
  1. aStatistical analysis was performed with Wilcoxon matched pairs signed-rank test, p values < 0.05 were considered to be significant.