Table 2 Efficacy and safety of early endoscopy versus medical therapy alone for management of acute upper gastrointestinal bleeding in acute coronary syndrome patients.
Non-EE group | EE group | p-value | ||||
|---|---|---|---|---|---|---|
ITT (n = 21) | PP (n = 19) | ITT (n = 22) | PP (n = 21) | ITT | PP | |
Failure of control bleeding, n (%) | 5 (23.81) | 3 (15.79) | 1 (4.55) | 0 (0.00) | 0.0002 | 0.058 |
Re-bleeding rate, n (%) | ||||||
3-day | 6 (28.57) | 4 (21.05) | 1 (4.55) | 0 (0.00) | 0.033 | 0.027 |
7-day | 2 (9.52) | 1 (5.26) | 4 (18.18) | 3 (14.29) | 0.425 | 0.342 |
SRH (GU/DU/Others), n (%) | 13 (61.90)/7 (33.33)/1 (4.8) | 11 (57.89)/7 (36.84)/1 (5.26) | 8 (36.36)/8 (36.36)/6 (27.27) | 7 (33.33)/8 (38.09)/6 (28.57) | 0.035 | 0.053 |
H. pylori positive, n (%) | 7 (33.33) | 5 (26.32) | 9 (40.91) | 9 (42.86) | 0.618 | 0.273 |
Hospital stay (days, mean ± SD) | 11.57 ± 5.67 | 11.05 ± 5.66 | 13.64 ± 10.99 | 13.14 ± 11.01 | 0.446 | 0.462 |
PRBC transfusion (units, mean ± SD) | ||||||
Before intervention | 1.90 ± 1.34 | 1.89 ± 1.32 | 2.45 ± 1.63 | 2.38 ± 1.63 | 0.234 | 0.217 |
After intervention | 2.76 ± 2.86 | 2.63 ± 2.99 | 0.77 ± 1.23 | 0.62 ± 1.02 | 0.005 | 0.006 |
Stent re-thrombosis within 6 months, n (%) | 6 (28.57) | 6 (31.58) | 5 (22.73) | 5 (23.81) | 0.670 | 0.583 |
Complications, n (%) | ||||||
Consciousness change | 4 (19.05) | 4 (21.05) | 2 (9.09) | 2 (9.52) | 0.358 | 0.308 |
Chest pain | 8 (38.10) | 7 (36.84) | 7 (31.82) | 7 (33.33) | 0.675 | 0.816 |
ECG ST-T changes | 8 (38.10) | 8 (42.11) | 2 (9.09) | 2 (9.25) | 0.024 | 0.018 |
Elevating TnT level | 14 (66.67) | 12 (63.16) | 10 (45.45) | 9 (42.86) | 0.169 | 0.199 |
Elevating CK-MB level | 0 (0.00) | 0 (0.00) | 1 (4.55) | 1 (4.76) | 0.323 | 0.335 |
Renal function impairment | 16 (76.19) | 14 (73.68) | 12 (54.55) | 11 (52.38) | 0.143 | 0.165 |
Arrhythmias | ||||||
Life threatening | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | NA | NA |
Non-life threatening | 13 (61.90) | 11 (57.89) | 16 (72.73) | 15 (71.43) | 0.461 | 0.370 |
Hypotension | 6 (28.57) | 6 (31.58) | 2 (9.09) | 2 (9.52) | 0.106 | 0.082 |
Tachypnea with hypoxemia | 4 (19.05) | 11 (57.89) | 9 (40.91) | 15 (71.43) | 0.124 | 0.370 |
Mortality | ||||||
Immediately | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | NA | NA |
Within 24 h | 0 (0) | 0 (0.00) | 1 (4.55) | 1 (4.76) | 0.335 | 0.335 |
Index admission | 6 (28.57) | 5 (26.32) | 3 (13.64) | 2 (9.52) | 0.239 | 0.163 |
