Figure 6
From: The human pathogenic 91del7 mutation in SLC34A1 has no effect in mineral homeostasis in mice
The 91del7 mutation has no effect on urinary and plasma parameters in young mice. (A, B) Phosphate and calcium concentration in spot urine obtained from 21 days old wild type (WT), heterozygous (Het) or homozygous (Hom) 91del7 mice. (C–E) Plasma phosphate, calcium and FGF-23 concentration in samples obtained from the same mice. (F, G) Expression of NaPi-IIa and NaPi-IIc in renal BBM from 21 days old pups from the three genotypes. The expression of the transporters was normalized to the corresponding β-actin. Data are presented as single values together with mean ± SEM (n = 3–7 per group). Significance was tested by one-way ANOVA with Bonferroni correction.
