Figure 8
From: The human pathogenic 91del7 mutation in SLC34A1 has no effect in mineral homeostasis in mice
The 91del7 mutation has no effect on adaption to dietary phosphate restriction. (A) Urinary phosphate/creatinine ratio during one day of standard diet (STD) and upon switch to low phosphate diet for 1–3 days. (B) Plasma phosphate after 3 days of low phosphate diet. (C) Urinary calcium/creatinine ratio during one day of standard diet (STD) and upon 3 days of low phosphate (low Pi) diet. (D) Plasma calcium levels after 3 days of low phosphate diet. All parameters were analyzed in samples obtained from 12 weeks old wild type (WT), heterozygous (Het) and homozygous (Hom) 91del7 mice. Data are presented as single values together with mean ± SEM (n = 7–8 per group). Significance was tested by one-way ANOVA with Bonferroni correction, *p ≤ 0.05.
