Figure 6 | Scientific Reports

Figure 6

From: Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers

Figure 6

Representative case of MCF-7 tumor. MR images: (a) T2WI, (b) sADC map (diffusion time, Td = 9 ms), (c) sADC map (Td = 27.6 ms), (d) ΔsADC200–1500 map, (e) APT imaging map, and whole tumor histological images: (f) H&E staining, (g) cellular area map, (h) Ki-67-positive cell map, (i) CD31 staining. (j) H&E staining on high power magnification (× 400). Yellow line squares with 200 μm sides were drawn on (j). The decrease of ADC with Td is evident. The dorsal part of the tumor shows high ΔsADC200–1500 and APT SI.

Back to article page