Figure 7
Representative case of MDA-MB-231 tumor. MR images: (a) T2WI, (b) sADC map (diffusion time, Td = 9 ms), (c) sADC map (Td = 27.6 ms), (d) ΔsADC200–1500 map, (e) APT imaging map, and whole tumor histological images: (f) H&E staining, (g) cellular area map, (h) Ki-67-positive cell map, (i) CD31 staining. (j) H&E staining on high power magnification (× 400). Yellow line squares with 200 μm sides were drawn on (j). The decrease of ADC with Td is evident. Central necrosis is apparent in regions with low ΔsADC200–1500 and APT SI.
