Figure 5

Dynamics of the DNA methylation across CpG sites of GPX7 in LGG and GBM tumors. (a) Heat-map showing the methylation levels of GPX7 among different CpGs sites (probes) integrating ethnicity, race, age, vital status and genomic regions of CpG sites from LGG; (b) Heat-map showing the methylation levels of GPX7 among different CpGs sites integrating ethnicity, race, age, vital status and genomic regions of CpG sites from GBM. (c) Pearson correlation between the degree of methylation (β-value) of each CpG site of GPX7 and its expression level (Log2 – TPM + 1) in LGG; Aggregation method: mean; (d) Pearson correlation between the degree of methylation (β-value) of each CpG site of GPX7 and its expression level (Log2 – TPM + 1) in GBM. Aggregation method: mean.