Figure 9

Functional enrichment analysis of GPX7-related genes in LGG and GBM cohorts from. TCGA. (a) Venn diagram of genes that positively (Left) and negatively (Right) correlated with GPX7 expression, showing shared genes in LGG and GBM. (b) Functional annotation using GSEA shows an overrepresentation of Gene Ontology (GO) terms of upregulated (blue) and downregulated (orange) genes co-expressed with GPX7 in LGG. (c) Functional annotation using GSEA shows an overrepresentation of Gene Ontology (GO) terms of upregulated (blue) and downregulated (orange) genes co-expressed with GPX7 in GBM. Dark blue and orange: FDR ⩽ 0.05; Light blue and orange: FDR > 0.05. Abbreviations: FDR: false discovery rate; GO: Gene ontology.