Figure 2

Leucine-rich repeat protein genes in the Mal2 locus influence fungus infection outcome. Graphs illustrate mortality curves of female mosquitoes after gene silencing followed or not with fungal infection. (A) Silencing of APL1A and APL1C gene expressions followed by infection with M. anisopliae, (B) Silencing of LRIM1 genes expression followed by infection with M. anisopliae, (C) Silencing of APL1A and APL1C gene expressions without fungal infection (D) Silencing of LRIM1 genes without fungal infection. P-values obtained from Cox Regression testing for difference between the given mortality curve and the dsGFP mortality curve are given in the legend. The y-axis coordinates on each panel represent the range of lifespan for the given condition. Error bars represent the variability between three independent biological replicates. For each tested gene, 50 mosquitoes were tested in each of three biological replicates.