Figure 4

Toll and Imd immune pathways protect Anopheles against fungal infection. Graphs illustrate mortality curves of female mosquitoes after gene silencing followed or not with fungal infection. (A) Silencing of CACTUS and REL2-F gene expression followed by infection with M. anisopliae (B) Silencing of CACTUS, REL2-F and REL2 gene expression without fungal infection (C) Silencing of REL2 gene expression followed by infection with M. anisopliae. P-values obtained from Cox Regression are given in brackets in the legend. Error bars represent the variability between three independent biological replicates. For each tested gene, 50 mosquitoes were tested in each of three biological replicates.