Table 1 Hazard ratio HR (99%CI) and lethal median time (LT50) of adult female A. coluzzi mosquitoes after gene silencing by dsRNA treatment.

From: Genetics and immunity of Anopheles response to the entomopathogenic fungus Metarhizium anisopliae overlap with immunity to Plasmodium

dsRNA

Fungus Infection

dsRNA

No Fungus Infection

HR

99% CI

p

LT50 ± S.E

n

HR

99% CI

p

LT50 ± S.E

n

Cactus

0.65

0.5–0.9

1.2 × 10–4

4 ± 0.14

150

Cactus

1.6

1.2–2.1

1.5 × 10–6

9 ± 0.5

150

Rel2-RHD

1.1

0.8–1.4

0.395

6 ± 0.24

164

Rel2-RHD

1.1

0.9–1.4

0.23

11 ± 0.5

211

Rel2-ANK

1.6

1.3–2.0

2.9 × 10–8

4 ± 0.09

292

Rel2-ANK

1.1

0.9–1.4

0.28

12 ± 0.5

355

APL1A

0.9

0.7–1.1

0.114

8 ± 0.34

445

APL1A

0.8

0.6–1.1

0.63

28 ± 0.7

218

APL1C

1.2

1.05–1.5

0.001

7 ± 0.28

433

APL1C

1.1

0.8–1.4

0.47

25 ± 1.3

182

LRIM1

1.3

1.1–1.5

2.8 × 10–5

5 ± 0.71

427

LRIM1

0.7

0.5–1.0

0.02

17 ± 1.0

110

TEP1

1.3

1.03–1.5

0.003

5 ± 0.10

191

TEP1

1.3

1.0–1.6

0.01

13 ± 0.5

207

TEP3

0.9

0.7–1.01

0.19

5 ± 0.12

459

TEP3

1.1

0.8–1.5

0.34

26 ± 0.6

127

TEP4

1.1

0.9–1.3

0.05

5 ± 0.03

418

TEP4

1.1

0.8–1.5

0.22

26 ± 0.3

182

  1. P-values (p) were obtained from the Cox regression model. n corresponds to the total number of mosquitoes used for the Kaplan–Meier.
  2. Significant values are in bold.