Table 2 Hazard ratio HR (99%CI) and lethal median time (LT50) of adult male A. coluzzii mosquitoes after gene silencing by dsRNA treatment.

From: Genetics and immunity of Anopheles response to the entomopathogenic fungus Metarhizium anisopliae overlap with immunity to Plasmodium

dsRNA

Fungus Infection

dsRNA

No Fungus Infection

HR

99% CI

p

LT50 ± S.E

n

HR

99% CI

p

LT50 ± S.E

n

APL1A

1.4

1.03–2.1

0.004

5 ± 0.1

187

APL1A

1.0

0.7–1.2

0.69

19 ± 0.5

200

APL1C

1.6

1.13–2.1

3.2 × 10–4

4 ± 0.1

153

APL1C

1.3

0.9–1.7

0.01

15 ± 1.0

187

LRIM1

1.0

0.7–1.6

0.735

4 ± 0.35

89

LRIM1

1.2

0.9–1.5

0.11

9 ± 0.6

166

TEP1

1.3

0.9–1.9

0.05

6 ± 0.13

98

TEP1

0.9

0.7–1.2

0.53

12 ± 0.9

157

TEP3

0.8

0.6–1.06

0.037

5 ± 0.27

132

TEP3

1.0

0.8–1.4

0.75

8 ± 0.5

157

  1. P-values (p) were obtained from the Cox regression model. n corresponds to the total number of mosquitoes used for the Kaplan–Meier survival tests for each condition.
  2. Significant values are in bold.
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