Table 3 Comparison of baseline characteristics according to the neurological outcomes at 6 months.
Variables | Good (N = 85) | Poor (N = 150) | p |
|---|---|---|---|
Age, years | 55.0 (44.5–65.0) | 64.0 (54.0–73.0) | < 0.001 |
Male, n (%) | 68 (80.0) | 107 (71.3) | 0.143 |
BMI, kg/m2 | 24.2 (22.1–26.4) | 22.9 (20.7–25.8) | 0.011 |
CRRT, n (%) | 10 (11.8) | 39 (26.0) | 0.010 |
ECMO, n (%) | 4 (4.7) | 4 (2.7) | 0.407 |
Preexisting illness, n (%) | |||
Coronary artery disease | 15 (17.6) | 25 (16.7) | 0.848 |
Congestive heart failure | 3 (3.5) | 4 (2.7) | 0.706 |
Hypertension | 28 (32.9) | 77 (51.3) | 0.006 |
Diabetes | 14 (16.5) | 60 (40.0) | < 0.001 |
Pulmonary disease | 1 (1.2) | 13 (8.7) | 0.020 |
Renal impairment | 6 (7.1) | 17 (11.3) | 0.289 |
Cerebrovascular accident | 7 (8.2) | 16 (10.7) | 0.547 |
Malignancy | 5 (5.9) | 9 (6.0) | 0.971 |
Cardiac arrest characteristics | |||
Witness of collapse, n (%) | 68 (80.0) | 82 (54.7) | < 0.001 |
Bystander CPR, n (%) | 63 (74.1) | 91 (60.7) | 0.037 |
Shockable rhythm, n (%) | 63 (74.1) | 28 (18.7) | < 0.001 |
Cardiac etiology, n (%) | 80 (94.1) | 85 (56.7) | < 0.001 |
Epinephrine, mg | 0 (0–2) | 3 (2–5) | < 0.001 |
Time to ROSC, min | 19.0 (14.0–26.0) | 37.0 (22.0–48.3) | < 0.001 |
Clinical characteristics after ROSC | |||
Glasgow Coma Scale | 5 (3–6) | 3 (3–3) | < 0.001 |
Lactate, mmol/L | 6.8 (4.0–9.4) | 9.7 (6.4–12.6) | < 0.001 |
Glucose, mg/dL | 251 (172–309) | 267 (204–360) | 0.061 |
PaO2, mmHg | 126 (84–201) | 136 (90–229) | 0.388 |
PaCO2, mmHg | 38.0 (31.6–46.5) | 50.5 (35.1–64.0) | < 0.001 |
SOFA score | 10 (7–11) | 12 (10–13) | < 0.001 |
Induction of TTM | |||
ROSC to TTM, min | 294 (226–366) | 258 (207–324) | 0.024 |
CT at start TTM, ℃ | 36.7 (36.0–37.3) | 35.5 (34.5–36.5) | < 0.001 |
Time to target temperature, min | 195 (133–287) | 103 (60–165) | < 0.001 |
Cooling rate, ℃/h | 0.93 (0.61–1.39), 78* | 1.5 (1.07–2.33), 127* | < 0.001 |
