Figure 1
From: Hydrogen-generating Si-based agent protects against skin flap ischemia–reperfusion injury in rats

Surgical procedure. (a) A 7 × 5 cm rectangular skin flap was designed on the abdomen of the rat. (b) The vascular pedicle of the flap was occluded for three hours in the I/R and I/R + Si groups. (c) The skin flap was re-sutured in the original position after a silicon sheet was placed between the flap and recipient bed. (d) Schematic illustration of the experimental protocol.