Table 1 Characteristics of patients with MINS and without MINS.

From: Risk factors, transcriptomics, and outcomes of myocardial injury following lower extremity revascularization

 

All

No MINS

MINS

p-value

(n = 226)

(n = 173)

(n = 53)

Age, median [IQR]

73 [66.0–81.0]

73.0 [66.0–80.0]

74.0 [68.0–82.0]

0.41

Female sex

79 (35.0%)

59 (34.1%)

20 (37.7%)

0.75

Race

   

0.38

White

141 (62.4%)

104 (60.1%)

37 (69.8%)

 

African American

48 (21.2%)

39 (22.5%)

9 (17.0%)

 

Asian

5 (2.2%)

3 (1.7%)

2 (3.8%)

 

Other

32 (14.2%)

27 (15.6%)

5 (9.4%)

 

Ethnicity

Hispanic/Latino

40 (17.7%)

35 (20.2%)

5 (9.4%)

0.11

BMI, median [IQR]

26.1 [23.0–29.7]

26.6 [23.5–29.7]

24.5 [22.4–28.9]

0.08

Smoking Status

   

0.83

Current

37 (16.4%)

29 (16.8%)

8 (15.1%)

 

Former

132 (58.4%)

102 (59.0%)

30 (56.6%)

 

Never

57 (25.2%)

42 (24.3%)

15 (28.3%)

 

Comorbidities

Hypertension

202 (89.4%)

158 (91.3%)

44 (83.0%)

0.14

Hyperlipidemia

163 (72.1%)

123 (71.1%)

40 (75.5%)

0.66

Diabetes mellitus

118 (52.2%)

85 (49.1%)

33 (62.3%)

0.13

Coronary artery disease

122 (54%)

81 (46.8%)

41 (77.4%)

0.0002

Prior myocardial infarction

64 (28.3%)

39 (22.5%)

25 (47.2%)

0.0009

Heart failure

47 (20.8%)

29 (16.8%)

18 (34.0%)

0.01

Prior stroke/TIA

41 (18.1%)

29 (16.8%)

12 (22.6%)

0.44

Obstructive sleep apnea

8 (3.5%)

8 (4.6%)

0 (0%)

0.24

Chronic obstructive pulmonary disease

39 (17.3%)

31 (17.9%)

8 (15.1%)

0.79

Malignancy

51 (22.6%)

40 (23.1%)

11 (20.8%)

0.86

Pre-operative medications

ACEi/ARB

122 (54.0%)

93 (53.8%)

29 (54.7%)

0.99

Beta-blockers

137 (60.6%)

100 (57.8%)

37 (69.8%)

0.16

Statin

185 (81.9%)

173 (80.3%)

46 (86.8%)

0.40

Laboratory dataa

Pre-operative troponin (ng/mL), median [IQR]

0.012 [0.012–0.026]

0.012 [0.012–0.014]

0.028 [0.012–0.05]

< 0.001

Cr (mg/dL), median [IQR]

1.00 [0.80–1.30]

1.00 [0.800–1.30]

1.10 [0.800–1.60]

0.26

Hgb (g/dL), median [IQR]

12.1 [10.4–13.5]

12.3 [10.5–13.7]

11.7 [10.0–13.2]

0.09

HbA1c (%),median [IQR]

6.5 [5.8–7.7]

6.35 [5.83–7.60]

7.05 [5.80–8.00]

0.41

LDL (mg/dL), median [IQR]

64.0 [50.0–91.0]

61.5 [49.5–87.5]

65.5 [55.0–97.8]

0.52

HDL (mg/dL), median [IQR]

40.0 [32.0–50.0]

39.0 [32.0–47.0]

40.0 [31.0–50.0]

0.68

  1. aLaboratory data available in a subset of participants: Pre-operative troponin n = 143 (No MINS n = 106, MINS: n = 37). Creatinine n = 224. Hgb n = 226. HbA1c n = 124. LDL n = 84. HDL n = 86.