Table 2 Surgical characteristics of lower extremity revascularization.

From: Risk factors, transcriptomics, and outcomes of myocardial injury following lower extremity revascularization

 

All

No MINS

MINS

p-value

(n = 226)

(n = 173)

(n = 53)

Peripheral artery disease classification

   

0.34

Stable peripheral artery disease

36 (15.9%)

30 (17.3%)

6 (11.3%)

 

Critical limb ischemia

187 (82.7%)

140 (80.9%)

47 (88.7%)

 

Femoral or popliteal aneurysm

3 (1.3%)

3 (1.7%)

0 (0%)

 

Disease presentation

ABI < 0.60

121 (53.5%)

94 (54.3%)

27 (50.9%)

0.78

Claudication

94 (41.6%)

81 (46.8%)

13 (24.5%)

0.006

Rest pain

94 (41.6%)

74 (42.8%)

20 (37.7%)

0.62

Ulceration

98 (43.4%)

68 (39.3%)

30 (56.6%)

0.039

Gangrene

58 (25.7%)

39 (22.5%)

19 (35.8%)

0.078

Approach

   

0.32

Open

114 (50.4%)

87 (50.3%)

27 (50.9%)

 

Endovascular (with Intervention)

77 (34.1%)

61 (35.3%)

16 (30.2%)

 

Hybrid

25 (11.1%)

16 (9.2%)

9 (17.0%)

 

Endovascular (no intervention)

10 (4.4%)

9 (5.2%)

1 (1.9%)

 

Operation time (h), median [IQR]

3.19 [2.17–4.72]

3.00 [2.07–4.41]

4.27 [2.52–5.42]

0.009

Intraoperative hemodynamics, median [IQR]a

Highest intra-op SBP (mmHg)

175 [152–199]

174 [153–198]

175 [149–200]

0.99

Highest intra-op DBP (mmHg)

81 [71–95]

82 [72–98]

79 [67–90]

0.12

Nadir intra-op SBP (mmHg)

90 [80–98]

89 [80–98]

90 [80–98]

0.94

Nadir intra-op DBP (mmHg)

40 [32–50]

40 [33–50]

39 [22–45]

0.04

Blood loss and anemia, median [IQR]a

Estimated blood loss (ml)

125 [50–300]

100 [50–250]

200 [75–500]

0.03

Post-op nadir hemoglobin (mg/dL)

8.9 [7.7–10.6]

9.2 [8.0–10.9]

7.9 [7.2–9.7]

< 0.001

Post-op creatinine (mg/dL)

1.0 [0.8–1.5]

1.0 [0.80–1.3]

1.3 [0.80–2.3]

0.006

  1. DBP diastolic blood pressure, SBP systolic blood pressure.
  2. aIntraoperative hemodynamic and laboratory data were available in a subset of patients.