Table 3 1 Over-represented Gene Ontology Classes, 2 Under-represented Gene Ontology Classes.
GO term | Count in selection | p value | FDR |
|---|---|---|---|
(1) | |||
Biological Process | |||
*Extracellular structure organization | 20 | 5.112E−10 | 3.400E−06 |
*Extracellular matrix organization | 19 | 6.497E−10 | 3.457E−06 |
*Collagen catabolic process | 10 | 4.219E−09 | 1.403E−05 |
*Collagen metabolic process | 10 | 1.564E−08 | 4.161E−05 |
*Extracellular matrix disassembly | 9 | 1.694E−07 | 3.757E−04 |
†Cell cycle arrest | 10 | 2.125E−06 | 3.141E−03 |
*Collagen fibril organization | 6 | 2.940E−06 | 3.910E−03 |
Response to acid chemical | 12 | 1.094E−05 | 1.120E−02 |
Response to toxic substance | 13 | 4.999E−05 | 4.290E−02 |
Autophagy | 7 | 9.546E−05 | 7.055E−02 |
Process utilizing autophagic mechanism | 7 | 9.546E−05 | 7.055E−02 |
Autophagosome assembly | 4 | 1.157E−04 | 7.327E−02 |
Autophagosome organization | 4 | 1.157E−04 | 7.327E−02 |
Cellular component disassembly | 13 | 1.059E−04 | 7.327E−02 |
Regulation of growth | 16 | 1.648E−04 | 9.963E−02 |
Molecular function | |||
*Extracellular matrix structural constituent | 10 | 1.384E−08 | 4.090E−05 |
Growth factor binding | 9 | 2.872E−06 | 3.910E−03 |
*Platelet-derived growth factor binding | 4 | 4.007E−06 | 5.077E−03 |
(2) | |||
Biological Process | |||
DNA metabolic process | 80 | 0.000E + 00 | 0.000E + 00 |
†Cell cycle | 103 | 0.000E + 00 | 0.000E + 00 |
†Mitotic cell cycle | 82 | 0.000E + 00 | 0.000E + 00 |
†DNA replication | 45 | 3.309E−39 | 1.775E−35 |
†Cell cycle process | 78 | 2.239E−38 | 9.004E−35 |
†Mitotic cell cycle process | 58 | 1.619E−33 | 4.341E−30 |
†DNA-dependent DNA replication | 28 | 4.829E−30 | 1.110E−26 |
DNA repair | 50 | 1.065E−29 | 2.285E−26 |
†DNA strand elongation involved in DNA replication | 20 | 7.749E−28 | 1.558E−24 |
Chromosome organization | 64 | 1.725E−27 | 3.264E−24 |
Molecular function | |||
Protein binding | 188 | 9.834E−13 | 5.455E−10 |
Catalytic activity, acting on DNA | 20 | 6.426E−12 | 3.335E−09 |
Nucleic acid binding | 104 | 1.667E−11 | 8.380E−09 |
Heterocyclic compound binding | 140 | 2.120E−10 | 9.745E−08 |
Organic cyclic compound binding | 141 | 2.508E−10 | 1.136E−07 |
Nucleotide binding | 77 | 1.431E−09 | 5.757E−07 |
Nucleoside phosphate binding | 77 | 1.460E−09 | 5.799E−07 |
DNA−dependent ATPase activity | 12 | 2.105E−09 | 8.064E−07 |
DNA binding | 77 | 4.162E−09 | 1.456E−06 |
Nucleoside−triphosphatase activity | 37 | 6.910E−09 | 2.340E−06 |
