Table 1 Epidemiology and SARS-CoV-2 reactive humoral immune response in healthcare workers after vaccination or prior COVID-19.

From: Predictors of impaired SARS-CoV-2 immunity in healthcare workers after vaccination with BNT162b2

 

Persons vaccinated by BNT162b2 (n = 1386)

Persons with prior SARS-CoV-2 infection, no vaccination (n = 45)

p

Median time after infection/vaccination (weeks)

8 (IQR 7–9)

20 (15–28)

< 0.0001

Median age (years)

45 (IQR 33–55)

33 (IQR 25–40.5)

0.0001

Female gender (n, %)

1025, 73.9%

27, 60%

0.04

Anti-SARS-CoV-2 IgG > 250 IU/ml (n, %)

1342, 96.9%

9, 20%

0.0001

Anti-SARS-CoV-2 IgG 100–250 IU/ml (n, %)

32, 2.3%

15, 33.3%

Anti-SARS-CoV-2 IgG 0.4–99 IU/ml (n, %)

10, 0.7%

20, 44.5%

Anti-SARS-CoV-2 negative (n, %)

2, 0.1%

1, 2.2%

  1. Data of vaccinated vs. convalescent healthcare workers were compared using Mann–Whitney test in case of continuous data, and by Fisher’s exact test in case of dichothomic data. Differences in assignment to one of the antibody concentration strata was analyzed by Chi-squared test.