Figure 1 | Scientific Reports

Figure 1

From: Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease

Figure 1

(A) Box and whisker plots showing microbial diversity of the mucosa-attached microbiome in CF and WT littermate mice. Boxplots display the median as the midline whilst the perimeters of the box display the 1st and 3rd quantiles of the data. Significance between groups is represented by asterisks; *P < 0.05; **P < 0.01; ***P < 0.001. (B) Linear mixed effects regression plots showing the relationship between Shannon diversity and small intestinal region (D; duodenum, J; jejunum, I; ileum). P-values and coefficient values are listed for each genotype. (C) Principal co-ordinates analysis (PCoA) plots of Jaccard distances for mucosa-attached microbiome samples from CF and WT littermate mice. Colours represent CFTR genotype and shapes represent small intestinal regions. The percentage of variation captured by each PCoA axis is indicated. P-values from ANOSIM analysis of Jaccard dissimilarity matrices are listed.

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