Figure 5 | Scientific Reports

Figure 5

From: Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease

Figure 5

Expression of enteroendocrine cells (EECs) in mouse ileal tissue. Quantification of cell numbers and representative images of (A) EECs with ChA positive cells stained green and (B & C) L-type EECs with GLP-1 and GLP-2 positive cells stained red in wild-type (blue circle, blue) and CFTR-null (Cftr−/−) (yellow inverted triangle, yellow) mice from group 1 and group 2. Nuclei are stained blue with 4',6-diamidino-2-phenylindole (DAPI). Box and whisker plots represent number of cells counted expressing ChA or GLP-1/2 as median ± 95% CI (n = 6 for each mice group). Statistical significance was determined by One-way ANOVA with differences between means identified using Tukey’s multiple comparison post hoc test; ****P < 0.0001. Images are 200 × magnified.

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