Figure 4
Venn diagrams of time and sex comparisons between males and females throughout renal IRI. Venn diagrams depicting the number of commonly regulated genes (A) in male and (B) in females at different time point comparisons: PS versus PR, WL versus PS and WL versus PR. Males showed an overall higher number of regulated genes. (C) Venn diagrams depicting the number of commonly regulated genes in the sex comparison at different time points: PR, PS and WL. Only two genes were commonly regulated one week following injury. Genes represented only in italic are down-regulated, whereas genes in bold and italic are up-regulated. Genes underlined are both up- and down-regulated in respective comparisons. Complete gene tables are available in supplemental material. adj. p value ≤ 0.25 and log |FC | ≥ 1. F female, M male, PR pre-ischemia, PS post-ischemia, WL one week later.
