Table 6 Summary of clusters and gene sets included in the pattern A for the renal IRI sex comparison.

From: Temporal and sex-dependent gene expression patterns in a renal ischemia–reperfusion injury and recovery pig model

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I-Immune cell regulation

Leucocyte cell–cell adhesion

T cell differentiation and activation in immune response

TNF production

INFy production

NF-kB signaling

Toll-like receptor signaling pathway (TLR3/TLR4)

Complement cascade

II-Morphogenesis development migration

Positive regulation of leucocyte chemotaxis and migration

Cellular response to chemokine

Positive regulation of mononuclear cell migration

III-Ion transport transmembrane

Cytosolic calcium

Calcium transport

Positive regulation of cytosolic calcium ion concentration

IV-Apoptotic intrinsic extrinsic

Intrinsic apoptotic signaling pathway

Intrinsic apoptotic signaling pathway by p53 class mediator

Regulation of signal transcription by p53

VI-Alcohol biosynthetic process

Steroid biosynthetic process

Regulation of cholesterol biosynthesis by SREBP (SREBF)

Metabolism of steroids

Lipid biosynthesis and metabolism

Inositol phosphate metabolic process

Cellular ketone metabolic process

VII-Steroid hormone response

Cellular response to hormone stimulus

Peptide

Estradiol

Cellular response to insulin stimulus (insulin receptor signaling pathway)

VIII-Regulation hormone secretion

Regulation of peptide, protein, hormone secretion and transport by cell