Figure 4
From: Efficient dendritic learning as an alternative to synaptic plasticity hypothesis
Experimental results supporting intra dendritic adaptation. (a) 60 micro-electrode array and scheme of an intracellular electrode (orange) and three nearby extracellular electrodes (i.e., pink, purple, and green) (left). Scheme of a patched neuron recorded intracellularly (orange), two stimulating extracellular electrodes (i.e., green and purple) adjacent to one dendrite, and third electrode (pink) near a different dendrite (right). (b) Two stimulating extracellular electrodes (i.e., green and purple) generate similar intracellularly recorded spike waveforms, which differ from the third one (pink). (c) Neuronal response latency, measuring the time lag between an extracellular stimulation and its corresponding evoked spike, for the green and purple extracellular electrodes, stimulated at 20 Hz. Response failures are denoted at − 1. The effective firing frequency is presented using sliding windows of 100 stimulations (black). (d) Training scheduling consists of 50 repeated pairs using δ = 4 ms and f = 5 Hz. (e) Intracellular recordings of threshold estimation by extracellularly stimulating five times at 1 Hz for each stimulation amplitude (bottom) using the green electrode, before and after training.
