Table 3 Results of hematological and biochemical measurements during the period six months before to one month after blood drawing and testing among individuals with positive and negative celiac antibody tests.

From: Biochemical abnormalities among patients referred for celiac disease antibody blood testing in a primary health care setting

 

Number of tests

Percentage with measurement

(%)

Women

Men

Celiac antibody positivea women

N = 4,613 tests in 513 women

Median (95% CI)

Celiac antibody negativea women

N = 309,658 tests in 37,218 women Median (95% CI)

Celiac antibody positivea men

N = 1,497 tests in 192 men

Median (95% CI)

Celiac antibody negativea men

N = 153,827 tests in 19,019 men

Median (95% CI)

Hemoglobin (mmol/L)

58,883

81.7

7.8 (7.8–7.9)

8.1 (8.1–8.1)

8.5 (8.4–8.7)

8.8 (8.8–8.8)

MCV ((Erythrocytes, mean corpuscular volume) (fL)

58,883

81.7

86.6 (85.9–87.4)

88.6 (88.6–88.7)

85.8 (84.7–87.0)

86.8 (86.7–86.9)

MCHC (Mean corpuscular hemoglobin concentration) (mmol/L)

14,044

22.4

20.3 (20.1–20.4)

20.7 (20.7–20.7)

20.8 (20.6–21.1)

21.0 (21.0–21.0)

Transferrin (µmol/L)

8,000

13.3

37.5 (35.7–39.3)

34.2 (34.0–34.3)

32.9 (31.2–34.7)

31.4 (31.2–31.6)

Transferrin (Fe-binding sites; P)—Iron

7,527

12.6

0.1 (0.1–0.1)

0.2 (0.2–0.2)

0.2 (0.2–0.3)

0.2 (0.2–0.2)

Ferritin (µg/L)

13,549

21.5

13.7 (11.3–16.7)

35.9 (35.2–36.6)

34.3 (25.2–46.8)

80.4 (78.0–83.0)

ALAT (Alanine transaminase) (U/L)

47,751

68.8

22.6 (21.6–23.6)

19.8 (19.7–19.9)

28.0 (25.9–30.3)

25.3 (25,1–25,5)

Alkaline phosphate (U/L)

43,964

63.9

87.2 (81.7–93.2)

74.1 (73.6–74.6)

113.3 (101.8–126.1)

100.1 (99.0–101.2)

Vitamin D (nmol/L)

28,599

43.8

60.3 (56.8–64.1)

58.9 (58.5–59.3)

66.8 (61.4–72.6)

55.1 (54.5–55.7)

ReticMCH (Reticulocyte, mean corpuscular hemoglobin) (fmol)

2,472

3.9

1.7 (1.6–1.7)

1.8 (1.8–1.9)

1.8 (1.8–1.9)

1.8 (1.8–1.9)

RDW (Erythrocytes volume, relative distribution width) (%)

58,882

81.7

13.8 (13.6–13.9)

13.2 (13.1–13.2)

13.5 (13.3–13.6)

13.2 (13.2–13.2)

Immunoglobulin A (g/L)

58,125

98.7

1.9 (1.8–2.0)

1.8 (1.8–1.8)

1.6 (1.5–1.8)

1.8 (1.8–1.8)

Cobalamin (pmol/L)

19,886

31.8

280.1 (261.2–300.4)

289.1 (287.1–291.2)

270.0 (244.5–298.1)

306.0 (303.1–308.8)

Folic acid (nmol/L)

2,839

4.7

12.9 (10.5–16.0)

17.5 (17.0–18.0)

8.9 (4.0–19.7)

16.5 (15.9–17.1)

C-reactive protein (CRP) (mg/L) b including < 

46,205

66.6

0.9 (0.6–1.3)

1.2 (1.1–1.2)

0.7 (0.3–1.4)

0.6 (0.5–0.6)

  1. aA positive celiac antibody test was defined as: IgA/IgG TTG of at least 7 U/ml or IgG DGP of at least 10 U/ml and a negative test was defined as IgA /IgG TTG under 7 U/ml and IgG DGP under 10 U/ml.
  2. bCRP was reported with ‘ < ’ in many cases; Low results were reported as < 5 mg/L (between December 2, 2002 and May 28, 2008) and < 4 (from May 29, 2008).
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