Figure 1 | Scientific Reports

Figure 1

From: Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis

Figure 1

Pharmacokinetic behavior of ALT-801 and semaglutide in C57Bl/6J mice following subcutaneous administration. Mice received a single s.c. injection of ALT-801 or semaglutide at 10 nmol/kg and key PK characteristics were calculated. Compared to semaglutide, for ALT-801 the data indicate a longer Tmax with a substantially lower Cmax and an overall delayed PK envelope, having a similar AUC.

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