Figure 3

Effects of treatment on liver fat content and liver weight. (A) Representative H&E-stained images of liver morphology at the end of treatment period for vehicle, semaglutide, elafibranor, and ALT-801 10 nmol/kg treated DIO-NASH animals (magnification 20×, scale bar = 100 µm). (B) Mean total liver fat content (mg). (C) Mean terminal liver weight (g). Data are expressed as mean ± SEM (n = 11–12). **p < 0.01, ****p < 0.0001 vs. vehicle control.