Figure 3
The sEH vaccine treatment reduced infarct size and fibrosis in cardiac tissue. (a) Cardiac sections were evaluated by Azan staining to determine the amount of fibrosis induced by MI after one week. The blue area indicates fibrosis due to myocardial infarction, and the red part indicates the non-infarcted area. (b) Infarcted area ratio was calculated by the fibrotic area / whole left ventricular area that shows the ratio of the infarcted tissue in the short axis sections. The vaccinated group had significantly reduced infarcted area. Saline group (n = 4), vaccinated group (n = 5), *P < 0.05. Percent myocardium infarcted was calculated in the saline and vaccinated groups.
