Table 1 Proteins that co-precipitated with two or more miRNAs or with ALG-1.
From: Functional identification of microRNA-centered complexes in C. elegans
Sequence name | Protein name | Average of NSAF ratiospulldown/control (spectral count) | Description | |||
|---|---|---|---|---|---|---|
let-7 | miR-58 | miR-2 | ALG-119 | |||
F48F7.1 | ALG-1 | 6 (88) | 19 (328) | 8 (73) | 573 (229) | Argonaute, miRISC component |
C06G1.4 | AIN-1 | 5 (25) | 16 (83) | 11 (28) | 125 (122) | miRISC component (GW182 homolog) |
C04E6.11 | C04E6.11 | 6 (86) | 5 (35) | 5 (7) | NA | Unknown |
T07D3.7 | ALG-2 | 115 (70) | 293 (292) | 105 (47) | NA | Argonaute |
B0261.2 | LET-363 | 5 (8) | 9 (8) | 47 (24) | NA | C. elegans Mtor |
T23F6.4 | RBD-1 | 20 (124) | 5 (55) | 27 (28) | NA | rRNA processing |
M88.5 | IMPH-1 | 9 (310) | 10 (237) | NA | 23 (39) | KH domain, RNA binding protein |
F26B1.2 | HRPK-1 | 146 (19) | 44 (4) | NA | 8 (14) | KH domain, RNA binding protein |
R10E4.2 | SUP-26 | 139 (20.5) | 43 (5) | NA | 113 (29) | Translational regulation |
Y48G8AL.6 | SMG-2 | 6 (43) | 45 (17) | NA | 9 (4) | NMD protein |
B0041.2 | AIN-2 | 22 (6) | 87 (83) | NA | NA | miRISC component |
Y49E10.15 | SNR-6 | 7 (41) | 5 (19) | NA | NA | Small nuclear ribonucleoprotein |
Y71F9B.4 | SNR-7 | 8 (42) | 260 (14) | NA | NA | Small nuclear ribonucleoprotein |
W08E3.1 | SNR-2 | 9 (48) | 5 (19) | NA | NA | Small nuclear ribonucleoprotein |
Y116A8C.42 | SNR-1 | 10 (55) | 4 (10) | NA | NA | Small nuclear ribonucleoprotein |
C52E4.3 | SNR-4 | 381 (31) | 4 (13) | NA | NA | Small nuclear ribonucleoprotein |
F43H9.3 | F43H9.3 | 4 (23) | 52 (8) | NA | NA | Predicted to enable nucleotidyltransferase activity |
ZC373.2 | ZC373.2 | 56 (5) | 43 (5) | NA | NA | Unknown |
W07E6.1 | NSUN-1 | 12 (5) | 67 (12) | NA | NA | Nop2 (NOP2)/SUN domain family member |
Y38C9A.2 | CGP-1 | 61 (22) | 52 (8) | NA | NA | Predicted to enable GTPase activity |
K10D2.3 | CID-1 | 16 (53) | 14 (6) | NA | NA | RNA 3′ uridylation |
W05F2.6 | W05F2.6 | 139 (21) | 114 (14) | NA | NA | Unknown |
T01H10.8 | LYST-1 | 41 (38) | 15 (12) | NA | NA | Lysosomal trafficking regulator protein |
K04G7.10 | RNP-7 | 36 (14) | 66 (5) | NA | NA | RNA binding protein |
Y37H2A.1 | Y37H2A.1 | 147 (25) | 65 (8) | NA | NA | Predicted to enable hydrolase activity |
F56B3.5 | ECH-5 | 94 (20) | 64 (12) | NA | NA | Enoyl-CoA hydratase |
F57H12.6 | F57H12.6 | 166 (12) | 4 (9) | NA | NA | Unknown |
F42A6.7 | HRPA-1 | 30 (5) | 14 (4) | NA | NA | RNA binding protein |
F25B5.7 | NONO-1 | 84 (14) | 100 (13) | NA | NA | Conserved nuclear protein |
H20J04.8 | MOG-2 | 161 (34) | NA | 114 (6) | NA | Enables U2 snRNA binding activity |
W02F12.5 | DLST-1 | 88 (75) | NA | NA | 18 (12) | DihydroLipoamide S-SuccinylTransferase |
F33D11.10 | F33D11.10 | 16 (7) | NA | NA | 29 (4) | RNA helicase activity |
ZC434.5 | EARS-1 | 14 (9) | NA | NA | 7 (4) | Glutamate-tRNA ligase activity |
H05C05.1 | H05C05.1 | 32 (9) | NA | NA | 12 (4) | Predicted to enable RNA strand annealing activity |
Y47D3B.10 | DPY-18 | NA | 15 (9) | NA | 23 (5) | Procollagen-proline 4-dioxygenase activity |
K02F2.1 | DPF-3 | NA | 58 (14) | NA | 42 (15) | Serine-type peptidase |
F52B5.3 | F52B5.3 | 6 (40) | NA | NA | 6 (4) | Predicted to enable ATP binding activity |
F18H3.3 | PAB-2 | NA | 20 (9) | NA | 5 (69) | Poly-A-binding protein |
K12H4.8 | DCR-1 | NA | 153 (84) | 27 (10) | 6 (5) | Small RNA processor |
F37C12.11 | RPS-21 | NA | NA | 89 (4) | 39 (33) | Ribosomal protein |
Y71F9AL.9 | Y71F9AL.9 | NA | NA | 45 (6) | 37 (7) | Unknown |
