Figure 4

Pitolisant enhances the proportion of synchronously active neuron pairs within excitatory responsive neuronal populations. (A) Proportions of cell pairs with synchronous activity do not differ between neuronal populations displaying excitatory and stable responses to saline treatment (p = 0.81, Fisher's exact test). (B) More cell pairs display synchronous activity within excitatory responsive neuronal populations to pitolisant treatment, compared with stable neuronal populations (**p = 6.2 × 10–5, Fisher's exact test).