Table 3 Cases with discordant results between intraoperative pathological diagnosis and OSNA assay.

From: One-step nucleic acid amplification for intraoperative diagnosis of lymph node metastasis in lung cancer patients: a single-center prospective study

Patient no.

Histological type

Lymph node station

IPD/OSNA*

CK19 mRNA (copies/μl)

4

Sq

11 (interlobar node)

Negative/micro

2700

15

Ad

11s (interlobar node)

Negative/micro

 < 250**

77

Ad

7 (subcarinal node)

Positive/Negative

 < 250

10L (hilar node)

Positive/negative

 < 250

94

Ad

11 (interlobar node)

Negative/negative

270

  1. Sq, squamous cell carcinoma; Ad, adenocarcinoma; IPD, interoperative pathological diagnosis.
  2. *In the OSNA assay, macro, micro, and negative showed > 5000, 250–5000, and < 250 copies/uL of CK19 mRNA, respectively.
  3. **Micrometastasis detected in diluted sample.
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