Figure 2 | Scientific Reports

Figure 2

From: In-vitro NET-osis induced by COVID-19 sera is associated to severe clinical course in not vaccinated patients and immune-dysregulation in breakthrough infection

Figure 2

Dysregulation of B-cells composition in peripheral blood of COVID-19 patients. Cell composition and expression differences between COVID-19 and healthy peripheral blood. UMAP of CD45+ leukocytes (A). Automatic prediction identifies different subsets in the B-cell -compartment (B). MFI expression changes in B-cells (rows: identified sub-populations; columns: antigen of interest (C). Memory-switched B cells and transitional B cells were lower in COVID-19 patients (red bars) than in healthy subjects (grey bars) (D). *p < 0.005, **p < 0.001, t-test.

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