Figure 2
From: Activation of NLRP3 inflammasome in stable chronic obstructive pulmonary disease
Plasma IL-1β concentration (a) and relative expression of IL1B, NLRP3 and CASP1 (b) in control and COPD subjects according to the severity of airflow obstruction. IL-1β interleukin-1beta, IL1B interleukin-1beta gene, NLRP3 nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 gene, CASP1 caspase-1 gene, COPD chronic obstructive pulmonary disease, GOLD Global Initiative for Chronic Obstructive Pulmonary Disease, C controls, G2 GOLD 2, G3 GOLD 3, G4 GOLD 4. Data were tested by Kruskal–Wallis test, and results were presented as a median and IQR. If P < 0.05, post-hoc test was performed. Connectors are showing the differences with P < 0.05 between the groups after post-hoc analysis.
