Figure 3
From: Activation of NLRP3 inflammasome in stable chronic obstructive pulmonary disease
IL-1β plasma concentration (a) and relative expression of IL1B, NLRP3 and CASP1 (b) in healthy subjects and COPD patients when subdivided into the groups based on smoking status. IL-1β interleukin-1beta, IL1B interleukin-1beta gene, NLRP3 nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 gene, CASP1 caspase-1 gene, COPD chronic obstructive pulmonary disease; 1: control non-smokers; 2: control smokers; 3: COPD non-smokers; 4: COPD former smokers; 5: COPD smokers. Data were tested by Kruskal–Wallis test, and results were presented as a median and IQR. If P < 0.05, post-hoc test was performed. Connectors are showing the differences with P < 0.05 between the groups after post-hoc analysis.
