Table 1 Basic characteristics, spirometry and common inflammatory markers of all participants included in the study.

From: Activation of NLRP3 inflammasome in stable chronic obstructive pulmonary disease

Parameter

Controls (n = 95)

COPD patients (n = 109)

P value

Age

64 (46–83)

65 (45–87)

0.069

Sex

Male

49

69

0.121

Female

46

40

FEV1 (L)

2.60 (2.12–3.19)

1.08 (0.69–1.60)

< 0.001

FEV1 (% pred.)

93.3 (86.4–104.2)

40.8 (27.9–61.7)

< 0.001

FVC (L)

3.35 (2.77–4.16)

2.28 (1.74–2.77)

< 0.001

FEV1/FVC (%)

80.6 (76.8–87.6)

51.3 (40.7–58.7)

< 0.001

CRP (mg/L)

1.47 (0.74–2.78)

2.34 (1.15–5.67)

< 0.001

FIB (g/L)

3.5 (3.1–3.8)

3.8 (3.4–4.5)

< 0.001

WBC (× 109/L)

6.14 (5.14–7.42)

7.57 (6.55–8.95)

< 0.001

Smoking status

Current smokers

47

37

< 0.001

Former smokers

0

90

Never smokers

48

10

  1. Age is presented as a median with minimum and maximum, and sex is presented as an absolute number.
  2. Other parameters were shown as a median with IQR.
  3. Data was analysed by Chi-squared or Mann–Whitney test, and results were considered statistically significant when P < 0.05.
  4. Significant values are in bold.
  5. FEV1 forced expiratory volume in the first second, FVC forced vital capacity, CRP C-reactive protein, FIB fibrinogen, WBC white blood cells, COPD chronic obstructive pulmonary disease.
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